Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021




Project Number:

I01BX002104-05A1
Title: PTH receptor Signaling and Diabetes-induced Bone Disease
Principal Investigator:

Teresita Bellido

Location: Little Rock, AR
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2018 - March 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$848,729
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Osteocytes play a critical role in bone homeostasis by regulating the production and activity of osteoblasts and osteoclasts; but less is known about osteocyte function in bone pathophysiology. Work by the PI during the previous funding period of this Merit award showed that activation of parathyroid hormone 1 receptor (PTH1R) signaling in osteocytes inhibits the expression of Sost/sclerostin, the osteocyte-derived inhibitor of bone formation, and increases in osteocytes the expression of RANKL,...



Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.