Office of Research & Development |
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Project Number: | IK6BX004200-01 |
Title: | BLR&D Research Career Scientist Award Application |
Principal Investigator: | Salman Azhar |
Location: | Palo Alto, CA |
Congressional District Code: | 18 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | April 2018 - March 2025 |
FY 2021 Funding Amount: | $236,386 |
Total Award Amount (all years): |
$1,627,064 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Numerous cross-sectional and longitudinal studies have established that circulating levels of testosterone decline with age in men. Likewise, human aging also results in a gradual decline in ovarian steroid production, a dramatic decline in adrenal androgens (DHEA, DHEAS), and alterations in cortisol and aldosterone production and secretion. Similar to humans, aging in experimental rodents is also associated with profound changes in the synthesis and secretion of steroid hormones, particularly t... |