Innate and acquired immune responses in human COPD
Congressional District Code:
Clinical Science R&D
July 2018 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Cigarette smoke-related lung diseases remain one of the most significant contributors to the shortening of life span and illness among our veterans. Over the past decade, our research has identified some of the critical mediators of inflammation that promotes the pathophysiology of human emphysema. Our initial discovery of activated T and B cells in the lungs of former smokers with emphysema, provided the rationale for pursing the role of acquired immunity that can perpetuate inflammation in the...