Office of Research & Development |
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Project Number: | I01CX000418-05A2 |
Title: | Rates and determinants of decreased bone health among HIV-infected patients |
Principal Investigator: | Roger Bedimo |
Location: | Dallas, TX |
Congressional District Code: | 30 |
Research Service: | Clinical Science R&D |
Project Period: | October 2018 - September 2023 |
FY 2021 Funding Amount: | $0 |
Total Award Amount (all years): |
$729,000 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: HIV and HCV infections are associated with an increased risk of osteoporotic fractures (OF). HIV/HCV co- infected subjects have a 3-fold increased fracture incidence compared to uninfected individuals, and 50% greater risk than HIV mono-infected. Despite being associated with this much higher fracture risk, HIV/HCV co- infection is not associated with lower bone mineral density (BMD) than HIV alone. The increased OF risk associated with HCV is likely mediated by micro-architectural changes that... |