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Project Number: | IK2RX002628-01A1 |
| Title: | Mimicking the Architecture and Modulus of Native Brain Tissue onto Neural Implants to Improve Biocompatibility |
| Principal Investigator: | Evon S. Ereifej |
| Location: | Ann Arbor, MI |
| Congressional District Code: | 11 |
| Research Service: | Rehabilitation R&D |
| Project Period: | March 2018 - February 2022 |
| FY 2021 Funding Amount: | $184,174 |
| Total Award Amount (all years): |
$730,898 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Electrical signals recorded from neurons by intracortical electrodes have been used by human patients to communicate with computers and to control robotic limbs. The signal quality and longevity of recordable signals are inconsistent. There is increasing evidence indicating that the neuro-inflammatory response may be a primary hurdle to consistently obtaining high quality recordings. Within the brain, cells are living in the elastic extracellular matrix (ECM) meshwork with 3D and high aspect rat... |