Office of Research & Development |
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Project Number: | I01BX003453-01A2 |
Title: | A novel treatment for bone fracture repair |
Principal Investigator: | Wenhan Chang |
Location: | San Francisco, CA |
Congressional District Code: | 12 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | October 2017 - September 2021 |
FY 2021 Funding Amount: | $165,000 |
Total Award Amount (all years): |
$1,253,748 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Bone fractures pose a significant problem for veterans who suffered from traumatic injury in the line of military duty or from prevalent osteoporotic diseases as a civilian. Intermittent (or daily) administration of parathyroid hormone (PTH) is the only FDA-approved pharmaceutics that produces osteoanabolism to treat osteoporosis. The osteoanabolic action of PTH is based on the ability of the hormone to alter systemic and local factors that promote osteoblast (OB) activity before its stimulation... |