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Funded Project Details - FY2021




Project Number:

I01BX002042-05
Title: Estrogen receptor-alpha effects on right ventricular vascular density and angiogenesis in pulmonary hypertension
Principal Investigator:

Timmy Lahm

Location: Indianapolis, IN
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: January 2018 - December 2021
FY 2021 Funding Amount: $156,771
Total Award Amount
(all years):
$746,524
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Pulmonary hypertension (PH) and right ventricular (RV) dysfunction are extremely common in veterans. Up to 80% of veterans with chronic obstructive pulmonary disease, pulmonary fibrosis, sleep disordered breathing or LV dysfunction (either systolic or diastolic) suffer from PH. Better RV function and female sex have been linked to improved survival in PH, and female patients exhibit better RV function than their male counterparts. This proposal builds on the scientific premise that even though R...



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