The Role of Deoxysphingolipids in Peripheral Neuropathy
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Biomedical Laboratory R&D
October 2017 -
FY 2021 Funding Amount:
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View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
There are an estimated 20 million people in the United States who have some form of peripheral neuropathy. Peripheral neuropathy also is the most prevalent complication of both type 1 and type 2 diabetes and affects approximately 60 to 70 percent of patients with diabetes. Clinically, diabetic neuropathy exhibits a pronounced similarity to the neuropathy of patients with hereditary sensory and autonomic neuropathy type 1 (HSAN1). HSAN1 patients exhibit elevated plasma levels of a newly identifie...