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Project Number: | I01BX003919-01A1 |
| Title: | The role of Nampt in age-associated persistent lung fibrosis |
| Principal Investigator: | Louise Hecker |
| Location: | Decatur, GA |
| Congressional District Code: | 3 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2017 - September 2022 |
| FY 2021 Funding Amount: | $248,800 |
| Total Award Amount (all years): |
$1,188,030 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: The pathophysiology of Idiopathic pulmonary fibrosis (IPF), a rapidly progressive and deadly fibrotic lung disease remains poorly understood. Aging is a well-recognized risk factor for IPF, and IPF disproportionately affects the aging veteran population. Given this shift in demographic, it is critical to understand the contribution of aging to the cellular/molecular mechanism(s) leading to the pathogenesis of age-related diseases, such as IPF. In resolving fibrosis, lung myofibroblasts (the key... |