Office of Research & Development |
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Project Number: | I01RX002100-01A2 |
Title: | Developing novel stem cell-based epigenetic approaches to treat hearing loss |
Principal Investigator: | Zhengqing Hu |
Location: | Allen Park, MI |
Congressional District Code: | 13 |
Research Service: | Rehabilitation R&D |
Project Period: | October 2018 - September 2022 |
FY 2021 Funding Amount: | $279,375 |
Total Award Amount (all years): |
$1,100,000 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary Auditory hair cells are mechanotransduction receptors that convey sound signals to the brainstem via spiral ganglion neurons (SGNs). However, hair cells are vulnerable to a number of insults, including noise, blast, aging, and traumatic brain injury. Adult mammalian hair cell loss is usually irreversible, causing permanent hearing loss and other inner ear disorders. Currently, there are no biological approaches to replenish human hair cells. The long-term goal of this project is... |