Molecular Analysis of Bacterial Adaptive Response to Host Reactive Species
Congressional District Code:
Biomedical Laboratory R&D
April 2017 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Infectious diarrhea afflicts a billion people a year and is responsible for 4% of all human deaths. Many of the 2,500 serovars of nontyphoidal Salmonella enterica are common causes of infectious diarrhea in the general population, active military servicemen and veterans. As is the case for Salmonella, the number of bacteria resistant to antibiotics is steadily increasing. Antibiotic resistance in Gram-negative bacilli is becoming a clinical problem of epic proportions with few therapeutic agents...