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Project Number: | I01BX003437-01A1 |
| Title: | Chemopotentiation by Low Dose Fractionated Radiation Therapy for disseminated intra-abdominal cancers |
| Principal Investigator: | France Carrier |
| Location: | Baltimore, MD |
| Congressional District Code: | 7 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2017 - June 2022 |
| FY 2021 Funding Amount: | $247,707 |
| Total Award Amount (all years): |
$1,287,322 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Whole abdominal radiotherapy (WART) is a primary method for managing gastrointestinal cancers that have disseminated into intra-abdominal tissues. While effective, this approach is limited since combination of WART with full-dose chemotherapy regimens increase toxicity to normal tissue. Recent studies have demonstrated a survival advantage in a novel treatment paradigm that allows for the safe use of full-dose systemic chemotherapy in combination with Low Dose Fractionated Radiotherapy (LDFRT).... |