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Funded Project Details - FY2021

Project Number:

Title: Relationship between circadian disruption, cardiac GH/IGF-1 signaling, and heart failure
Principal Investigator:

Stuart J. Frank

Location: Birmingham, AL
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2017 - March 2022
FY 2021 Funding Amount: $82,500
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Cardiovascular disease (CVD) is a major cause of mortality in the U.S. Among CVDs, heart failure (HF) is a sig- nificant public health burden contributing not only to human suffering, but also to increasing healthcare expend- itures. CVDs arise in the setting of complex gene-environment interactions; the underlying genetics within an in- dividual influences how environmental and hormonal stimuli and stresses affect cardiac function and cause path- ology. The cardiomyocyte circadian clock is a ge...

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