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Project Number: | I01BX003718-01A1 |
| Title: | Relationship between circadian disruption, cardiac GH/IGF-1 signaling, and heart failure |
| Principal Investigator: | Stuart J. Frank |
| Location: | Birmingham, AL |
| Congressional District Code: | 7 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2017 - March 2022 |
| FY 2021 Funding Amount: | $82,500 |
| Total Award Amount (all years): |
$686,100 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Cardiovascular disease (CVD) is a major cause of mortality in the U.S. Among CVDs, heart failure (HF) is a sig- nificant public health burden contributing not only to human suffering, but also to increasing healthcare expend- itures. CVDs arise in the setting of complex gene-environment interactions; the underlying genetics within an in- dividual influences how environmental and hormonal stimuli and stresses affect cardiac function and cause path- ology. The cardiomyocyte circadian clock is a ge... |