Office of Research & Development |
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Project Number: | I01BX000319-09 |
Title: | Ischemic Kidney Injury and Kidney Repair |
Principal Investigator: | Zheng Dong |
Location: | Augusta, GA |
Congressional District Code: | 10 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | October 2017 - September 2021 |
FY 2021 Funding Amount: | $165,000 |
Total Award Amount (all years): |
$753,000 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Acute kidney injury (AKI) is a major renal disease that is associated with high mortality and prevalence. Recent work further indicates that AKI contributes to the development and progression of chronic kidney disease (CKD). However, the mechanism of AKI-CKD transition is largely unclear. Renal interstitial fibrosis is a key pathological event in maladaptive kidney repair following AKI and its progression to CKD. While interstitial fibrosis may involve various cell types in post-AKI kidneys, the... |