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Project Number: | I01BX001919-05 |
| Title: | Development of Human Asparaginase for Cancer Therapy |
| Principal Investigator: | Arnon Lavie |
| Location: | Chicago, IL |
| Congressional District Code: | 7 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | July 2017 - June 2022 |
| FY 2021 Funding Amount: | $43,886 |
| Total Award Amount (all years): |
$1,129,718 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary: This application will address the unmet need for superior treatment outcomes for adults with acute lymphoblastic leukemia (ALL), and will develop the tools needed for personalized treatment to allow a more expanded use of the unique anti-cancer drug called L-asparaginase. Unlike pediatric ALL, a disease with a cure rate of >90%, the cure rate of adult ALL is <40%. One significant difference between the treatment of pediatric and adult ALL patients is that only the pediatric regi... |