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Funded Project Details - FY2021




Project Number:

I01BX003724-01A1
Title: Endocrine Actions of Sclerostin
Principal Investigator:

Ryan C Riddle

Location: Baltimore, MD
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2017 - March 2021
FY 2021 Funding Amount: $207,279
Total Award Amount
(all years):
$1,139,645
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

The skeleton, populated by large numbers of osteoblasts and osteocytes, requires a constant supply of energy-rich molecules to fuel the: synthesis, deposition, and mineralization of bone matrix during bone modeling and remodeling. As a result, studies performed over the last decade have expanded our understanding of the physiologic functions of bone beyond locomotion, mineral ion storage, and protection of vital organs to now include the secretion of hormones that contribute to the regulation of...



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