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Project Number: | I01RX001818-01A2 |
| Title: | Erythromycin-doped nanofiber coating to increase implant longevity |
| Principal Investigator: | Weiping Ren |
| Location: | Allen Park, MI |
| Congressional District Code: | 13 |
| Research Service: | Rehabilitation R&D |
| Project Period: | January 2017 - December 2020 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$711,479 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Failure of osseointegration (direct anchorage of an implant by bone formation at the bone-implant surface) and implant infection are the two main causes of implant failure and loosening. There is an urgent need for orthopedic implants that both promote rapid osseointegration and prevent bacterial colonization, particularly when placed in bone compromised by disease or the physiology of the patients. The goal of this study is to develop a bactericidal “bone-like” nanofiber (NF) coating to enhance... |