Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites
Veterans Benefits and Health Care About VA Find a VA Location

Office of Research & Development

 print icon sign up for VA Research updates

Funded Project Details - FY2021




Project Number:

I01RX002274-01A1
Title: Tissue Engineered Total Disc Replacement in a Large Animal Model
Principal Investigator:

Harvey Smith

Location: Philadelphia, PA
Congressional District Code: 2
Research Service: Rehabilitation R&D
Project Period: April 2017 - March 2021
FY 2021 Funding Amount: $137,489
Total Award Amount
(all years):		 $1,099,920
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER

Excerpt:

Title: Tissue Engineered Total Disc Replacement in a Large Animal Model The objective of this project is to develop a tissue-engineered construct including an engineered nucleus pulposus and annulus fibrosus to treat degenerative changes of the intervertebral disc (IVD). In Specific Aim 1, we will build on our preliminary small animal studies to construct cell- seeded DAPS whose geometric dimensions are comparable to human and goat IVDs. A novel compression-torsion bioreactor and simulated ex vi...


Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.