Office of Research & Development |
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Project Number: | I01CX001434-01A2 |
Title: | Surgical Studies on the Role of MicroRNAs in Esophageal Cancer |
Principal Investigator: | James Donahue |
Location: | Birmingham, AL |
Congressional District Code: | 7 |
Research Service: | Clinical Science R&D |
Project Period: | January 2017 - December 2021 |
FY 2021 Funding Amount: | $110,250 |
Total Award Amount (all years): |
$816,750 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Background: Despite significant reductions in the morbidity and mortality associated with esophagectomy, survival for patients with esophageal cancer remains dismal. In most patients, adjunctive therapies including chemotherapy and radiation are beneficial. In fact, patients who achieve a complete pathologic response (pCR) after treatment with chemotherapy and radiation followed by esophagectomy often experience greatly improved survival. Unfortunately, the percentage of patients who currently a... |