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Funded Project Details - FY2021




Project Number:

I01BX003303-01A2
Title: Slowing Proteotoxic Neurodegeneration by Boosting Mitochondrial Bioenergetics and Recruiting a Novel Class of Chaperones
Principal Investigator:

Antonio Barrientos

Location: Miami, FL
Congressional District Code: 18
Research Service: Biomedical Laboratory R&D
Project Period: January 2017 - December 2020
FY 2021 Funding Amount: $129,435
Total Award Amount
(all years):
$1,082,402
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

One of the major challenges for the U.S. Department of Veterans Affairs is to extend the health-span of the veterans and their families as their physical and/or cognitive performance capabilities decline with age. Human neurodegenerative protein misfolding disorders or proteinopathies, are associated with abnormal protein depositions in brain neurons. They include polyglutamine (polyQ) disorders such as Huntington's disease and α-synucleinopathies such as Parkinson's disease. Disclosing the basi...



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