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Project Number: | I01BX003744-01 |
| Title: | Pathways regulating adult pancreatic beta cell replication |
| Principal Investigator: | Maureen Gannon |
| Location: | Nashville, TN |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2016 - March 2021 |
| FY 2021 Funding Amount: | $115,624 |
| Total Award Amount (all years): |
$1,197,798 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary/Abstract Type 2 diabetes (T2D) disproportionately affects the Veteran population: while 9% percent of the total US population has T2D, 25% of the Veteran population suffers from this disease. Adult β cell mass normally increases via replication in response to insulin resistance, but failure of β cell proliferation plus increased β cell death lead to T2D. T2D incidence increases with age, in part due to a decreased ability of β cells to respond to proliferative cues as they get ol... |