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Funded Project Details - FY2021

Project Number:

Title: Tunable Assembly of Regulatory Immune Signals to Promote Myelin-specific Tolerance
Principal Investigator:

Christopher Jewell

Location: Baltimore, MD
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: July 2017 - June 2022
FY 2021 Funding Amount: $241,024
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


During autoimmunity, the body identifies and attacks “self” molecules as foreign. Current therapies employ broad immunosuppression, which is beneficial to patients, but can leave them immunocompromised. This limitation, along with the lack of cures, has sparked intense interest in strategies that could control autoimmunity with vaccine-like specificity, leaving the rest of the immune system intact. Several pre-clinical reports and clinical trials have investigated this theory to combat multiple...

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