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Project Number: | I01BX003265-01A1 |
| Title: | MIF-mediated Mechanisms in Emphysema |
| Principal Investigator: | Patty J. Lee |
| Location: | Durham, NC |
| Congressional District Code: | 3 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2017 - September 2021 |
| FY 2021 Funding Amount: | $165,825 |
| Total Award Amount (all years): |
$680,000 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Chronic Obstructive Pulmonary Disease (COPD) has reached epidemic proportions but specific therapies do not exist. Emphysema is a major subset of COPD and is defined histopathologically as enlarged airspaces, which result in ineffective gas exchange. Aside from age, cigarette smoke (CS) exposure is one of the most common identifiable risk factors for COPD. Understanding mechanisms of CS-induced emphysema will allow us to develop effective therapies for a potentially modifiable lung disease that... |