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Project Number: | I01RX000458-05A1 |
| Title: | Role of TPH2 and 5HT Neuronal Loss in Non-motor Symptoms of Parkinson's |
| Principal Investigator: | Donald M. Kuhn |
| Location: | Allen Park, MI |
| Congressional District Code: | 13 |
| Research Service: | Rehabilitation R&D |
| Project Period: | July 2016 - December 2020 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$1,081,400 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary/Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease and affects about 1% of the population aged 65 and older. It is often thought of as a condition that selectively targets the dopamine (DA) neuronal system for destruction, giving rise to the well-known motor deficits of tremor, bradykinesia, rigidity and postural instability. The first-line pharmacological treatment for PD is L-DOPA, which is intended to replenish brai... |