Office of Research & Development |
  |
Talk to the Veterans Crisis Line now
An official website of the United States government
Project Number: | I01RX001455-01A2 |
| Title: | MicroRNA regulation of angiogenesis in aging |
| Principal Investigator: | Qingde Wang |
| Location: | Pittsburgh, PA |
| Congressional District Code: | 14 |
| Research Service: | Rehabilitation R&D |
| Project Period: | January 2017 - September 2022 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$1,099,999 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary Impaired vascular repair/angiogenesis is a major clinical problem in aged patients that often leads to ischemic peripheral artery and cardiovascular diseases. Recent studies have focused on strategies to improve aged cells’ angiogenesis capability and subsequent tissue repair. MicroRNAs (miRNAs) have emerged as crucial regulators of vascular function. We propose that altered expression of miRNAs in hind limbs during aging contributes to the age-dependent decline in vascular funct... |