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Funded Project Details - FY2021




Project Number:

I01RX001455-01A2
Title: MicroRNA regulation of angiogenesis in aging
Principal Investigator:

Qingde Wang

Location: Pittsburgh, PA
Congressional District Code: 14
Research Service: Rehabilitation R&D
Project Period: January 2017 - September 2022
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
$1,099,999
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Project Summary Impaired vascular repair/angiogenesis is a major clinical problem in aged patients that often leads to ischemic peripheral artery and cardiovascular diseases. Recent studies have focused on strategies to improve aged cells’ angiogenesis capability and subsequent tissue repair. MicroRNAs (miRNAs) have emerged as crucial regulators of vascular function. We propose that altered expression of miRNAs in hind limbs during aging contributes to the age-dependent decline in vascular funct...



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