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Project Number: | I01CX000623-05 |
| Title: | Role of Gfi-1 in Myeloma Bone Disease |
| Principal Investigator: | Attaya Suvannasankha |
| Location: | Indianapolis, IN |
| Congressional District Code: | 7 |
| Research Service: | Clinical Science R&D |
| Project Period: | July 2016 - December 2020 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$707,250 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): Bone disease occurs in over 80% of Multiple Myeloma (MM) patients and is characterized by severe osteolytic bone destruction accompanied by profoundly suppressed or absent bone formation that has devastating consequences for patients These consequences include pathologic fractures, severe bone pain and derangements in mineral metabolism that negatively impact survival, performance status and quality of life. Adhesive interactions between bone marr... |