Office of Research & Development |
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Project Number: | IK2BX003196-01A1 |
Title: | Mechanisms of age-related cognitive impairment in male and female rats after mTBI |
Principal Investigator: | Ashley M Fortress |
Location: | Pittsburgh, PA |
Congressional District Code: | 10 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | May 2016 - April 2021 |
FY 2021 Funding Amount: | $0 |
Total Award Amount (all years): |
$630,373 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): Over 90% of all traumatic brain injuries (TBI) sustained by military populations are classified as mild TBI or moderate TBI, with the vast majority being mild TBI. Mild or moderate TBI in early life is associated with memory impairments later in life, suggesting that TBI during early adulthood can exacerbate age-related changes that occur later in life. Despite this, the neurobiological mechanisms of memory impairment following TBI are not fully u... |