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Project Number: | I01BX002876-01A2 |
| Title: | Neuronal Subtype Specific Epigenetic Regulation in Schizophrenia |
| Principal Investigator: | Stella Plevan (Dracheva) |
| Location: | Bronx, NY |
| Congressional District Code: | 13 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | April 2016 - March 2021 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$723,350 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): Several candidate risk genes and genomic regions for schizophrenia (SZ) have been identified as well as numerous environmental risk factors. The etiology of SZ, however, remains unknown. Some of the environmental influences may act through epigenetic mechanisms (e.g., DNA methylation and histone modifications) which can alter gene expression by influencing functional DNA elements (e.g., promoters or enhancers), thus altering transcription. Accumul... |