Office of Research & Development |
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Project Number: | I01BX002926-01A1 |
Title: | Palladium based nanoparticles for the treatment of advanced melanoma |
Principal Investigator: | Jack L. Arbiser |
Location: | Decatur, GA |
Congressional District Code: | 5 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | January 2016 - December 2020 |
FY 2021 Funding Amount: | $0 |
Total Award Amount (all years): |
$698,750 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant): Iron oxide nanoparticles are novel agents for the delivery of high concentrations of therapeutics to areas with leaky blood vessels. The focus of this initial proposal is the nanoparticle mediated delivery of a novel therapeutic agent, Tris DBA Palladium for the prevention and treatment of genetically diverse melanoma. We propose to assess the efficacy of IGF-1 targeted nanoparticles containing Tris DBA Palladium to mice carrying genetically diver... |