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Project Number: | I01BX003284-01 |
| Title: | Mechanisms of ventilatory adaptations to chronic hypercapnia |
| Principal Investigator: | Hubert V. Forster |
| Location: | Milwaukee, WI |
| Congressional District Code: | 4 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | January 2016 - January 2021 |
| FY 2021 Funding Amount: | $24,530 |
| Total Award Amount (all years): |
$1,119,286 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: DESCRIPTION (provided by applicant) Chronic hypercapnia due to lung or neuromuscular disease or iatrogenic intervention is common in Veteran's Affairs patients. Permissive hypercapnia from low volume mechanical ventilation is standard care for protection against barotrauma in the lung, but the effects of chronic hypercapnia on the brain are largely unknown. Our goal is to understand the time course and molecular mechanisms of the central nervous system's response to chronic hypercapn... |