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Funded Project Details - FY2021




Project Number:

I01BX003035-01
Title: HuR regulates TDP-43 and FUS: implications for ALS pathogenesis
Principal Investigator:

Liang Lu

Location: Houston, TX
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: April 2016 - September 2021
FY 2021 Funding Amount: $30,000
Total Award Amount
(all years):
$763,255
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder in which selective loss of motor neurons leads to fatal paralysis. Military personnel are nearly twice as likely to develop ALS, regardless of the branch of service or the time period served, thus its impact on veteran health care is enormous. However, little is known about the pathogenesis of ALS, and there is no cure or effective treatment. Discovery of mutations in SOD1 has been the driving force in ALS research f...



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