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Funded Project Details - FY2021

Project Number:

Title: Molecular mechanisms of antibiotic resistance in Acinetobacter baumannii
Principal Investigator:

David S Weiss

Location: Decatur, GA
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: January 2016 - December 2021
FY 2021 Funding Amount: $21,806
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


ABSTRACT Objectives Antibiotic resistance in bacterial pathogens is an immense and rapidly growing medical problem affecting the health of veterans and the broader population. Compounding this problem is the lack of new drugs, which together threaten our return to the pre-antibiotic era. The objective of this study is to molecularly and functionally characterize a novel and critical mediator of resistance to last-line polymyxin antibiotics, FlpR, which is conserved in numerous medically relevant...

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