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Project Number: | I01RX001213-01A2 |
| Title: | Cartilage response to compression injury: A platform for therapeutics discovery |
| Principal Investigator: | George R Dodge |
| Location: | Philadelphia, PA |
| Congressional District Code: | 2 |
| Research Service: | Rehabilitation R&D |
| Project Period: | August 2014 - January 2021 |
| FY 2021 Funding Amount: | $0 |
| Total Award Amount (all years): |
$1,093,978 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: AbstractThis project seeks to rapidly advance the state of the art in understanding anddiscovering new therapeutic agents for the treatment of traumatic injury to cartilage.Excessive loads and blunt force trauma are responsible for initiating and furtheringcartilage pathology and eventually an "under repaired" joint surface that progressivelydeteriorates and functionally fails. Indeed, patients with focal cartilage defects havequality of life scores comparable to those with severe osteoarthritis... |